Wrinkles mainly happen on the parts of the body that get the most sun exposure, including the face, neck, the backs of the hands, and the tops of the forearms.

There are several ways to minimize the appearance of wrinkles and even remove them.

• Retinoids (tretinoin, Altreno, Retin-A, ). Among medical treatments, this is by far the most proven and effective way of bettering signs of aging such as uneven pigmentation, roughness, and wrinkling. At first, these medications may cause redness and peeling. Although this can be unpleasant, improvement comes when the peeling stops.
• Alpha-hydroxy acids. These are the so-called “fruit acids” and include glycolic and lactic acid. Preparations containing these fruit acids are quite safe and cause no more than mild and temporary irritation. The improvement they produce is, however, relatively subtle.
• Antioxidants. These include vitamins A, C, and E, as well as beta-carotene. Products that have antioxidants may provide some sun protection (though you should still wear sunscreen) and mildly improve wrinkles.
• Moisturizers. These may temporarily make wrinkles look less noticeable. Ads often say that they “reduce the appearance of fine lines.” But they don’t make those lines go away permanently.
• Glycolic acid peels. These superficial peels can make a very slight difference in the intensity of fine wrinkles.
• Deeper peels. These peels use ingredients like phenol, salicylic acid, TCA and trichloroacetic acid and penetrate somewhat deeper into the skin. These deeper peels do a better job of smoothing fine lines. In general, however, the deeper the peel, the greater the chance of side effects, such as scarring and changes in skin color. Such peels can be uncomfortable, so ask ahead of time what to expect.
• Dermabrasion. This procedure “sands” the skin. Depending a great deal on the skill and experience of the professional who does it, dermabrasioncan make a big difference. Side effects, including scarring and permanent changes in skin color, are also possible.
• Laser resurfacing. Doctors can use lasers to stimulate the skin’s production of collagen, which plumps up skin. There are different types of lasers, and you should ask your doctor about how many treatments you’ll need, how much “down time” you’ll need for your skin to heal, and any risks.
• Ultrasound therapy. The FDA has approved a technique called Ultherapy which uses ultrasound in a noninvasive technique to lift and tighten skin on the face, neck, and chin. It can also be used on wrinkles on the chest area.
• Injections. Some injections, including Botox, relax muscles that produce the “frown lines” on the forehead, fine lines around the eyes, and other wrinkles. Improvement lasts several months and must be repeated to sustain improvement. Others are wrinkle fillers. You should only get injections from a doctor.

Factors that promote wrinkling include:

• Smoking
• skin type (people with light-colored skin and blue eyes are more susceptible to sun damage)
• Heredity (some families wrinkle more)
• Sun exposure